Protein Info for SMc04341 in Sinorhizobium meliloti 1021

Annotation: amino acid-binding periplasmic protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF04069: OpuAC" amino acids 25 to 303 (279 residues), 167.4 bits, see alignment E=2.4e-53

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 100% identity to sme:SMc04341)

Predicted SEED Role

"PUTATIVE AMINO ACID-BINDING PERIPLASMIC PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92NV4 at UniProt or InterPro

Protein Sequence (314 amino acids)

>SMc04341 amino acid-binding periplasmic protein (Sinorhizobium meliloti 1021)
MGRGREFLCAAALALAVAAPAAAADLVIAMPPWPSGQAAANILKLGIAKKFSLEAEVREL
GTLTAFIGLEKGEVDIQPEVWRPNFDELVRKFVTEKGVVTLSERAVPAWQGICATPEAAA
TIKSVADLGDPAKTKILDTDGDGRGEMWIGAAEWLSTGIERARAAGYGYAANLTLVEAKE
EVAMAAVDAAIATARPMVFYCYAPHHVFKLHQISRLEEPPHDPAKWKIAPPNDPLWVSKS
SAATAWDAGQFQIGYATAFAKKHPEVAQFLQKVDFSPDEVTAMSYALEVERQAPADYARK
WVESHAERIDGWAK