Protein Info for SMc04317 in Sinorhizobium meliloti 1021

Annotation: iron-binding periplasmic protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13531: SBP_bac_11" amino acids 32 to 279 (248 residues), 90.7 bits, see alignment E=2.5e-29 PF01547: SBP_bac_1" amino acids 36 to 272 (237 residues), 91 bits, see alignment E=2.9e-29 PF13416: SBP_bac_8" amino acids 40 to 294 (255 residues), 100.3 bits, see alignment E=3.5e-32 PF13343: SBP_bac_6" amino acids 75 to 305 (231 residues), 100.9 bits, see alignment E=1.7e-32

Best Hits

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 100% identity to smk:Sinme_2032)

Predicted SEED Role

"Ferric iron ABC transporter, iron-binding protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7APD0 at UniProt or InterPro

Protein Sequence (326 amino acids)

>SMc04317 iron-binding periplasmic protein (Sinorhizobium meliloti 1021)
MKTLLPAVAAALVAGLLSTAAFAESLVLYTSQPNEDAQATVDAFEAANPGVEVEWVREGT
TKIMAKLMAEIEAGNPVADVLLIADTVTMQRLKEAGHLMPYKSPEAAAYDASLFDGEGAY
YSTKMITTGIIYNASASMKPTGWQDLAKPEAKGLVTMPSPLTSGAALIHAQTLAGIDGLG
WDYYKALAENGATAAGGNGGVLKAVATGEKAYGMVVDFMAIRERAKGAPVEFVFPAEGVS
AVTEPVAVLKTARNPETAKKFVDFLLSEEGQQVAVKMGYIPARDGMALPAGFPARETIKV
LPVDAAEAVKNSEADLKTFSGIFGTN