Protein Info for SMc04257 in Sinorhizobium meliloti 1021

Updated annotation (from data): ABC transporter for D-Cellobiose and D-Salicin, permease component 1
Rationale: Specific phenotypes on D-Cellobiose; D-Salicin.
Original annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 104 to 124 (21 residues), see Phobius details amino acids 133 to 155 (23 residues), see Phobius details amino acids 163 to 185 (23 residues), see Phobius details amino acids 210 to 233 (24 residues), see Phobius details amino acids 271 to 293 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 120 to 298 (179 residues), 60.6 bits, see alignment E=8.5e-21

Best Hits

KEGG orthology group: K02026, multiple sugar transport system permease protein (inferred from 100% identity to smk:Sinme_1898)

Predicted SEED Role

"ABC-type sugar transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92P66 at UniProt or InterPro

Protein Sequence (305 amino acids)

>SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 (Sinorhizobium meliloti 1021)
MAAAYETAPGGPMAGPRGRKPRRTLSRRNIIVYGTLIVVALYYLLPLYVMIVTSLKGMPE
IRVGNIFAPPLEITFEPWVKAWAEACTGLNCDGLSRGFWNSVRITVPSVIISIAIASVNG
YALANWRFKGADLFFTILIVGAFIPYQVMIYPIVIVLREMGVYGTLTGLIIVHTIFGMPI
LTLLFRNYFAGLPEELFKAARVDGAGFWTIYFKIMLPMSLPIFVVAMILQVTGIWNDFLF
GVVFTRPEYYPMTVQLNNIVNSVQGVKEYNVNMAATILTGLVPLTVYFVSGRLFVRGIAA
GAVKG