Protein Info for SMc04231 in Sinorhizobium meliloti 1021

Annotation: excinuclease ABC subunit B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 985 TIGR00631: excinuclease ABC subunit B" amino acids 159 to 816 (658 residues), 1020.5 bits, see alignment E=0 PF04851: ResIII" amino acids 166 to 291 (126 residues), 45.5 bits, see alignment E=2.4e-15 PF00270: DEAD" amino acids 173 to 236 (64 residues), 26.3 bits, see alignment 1.7e-09 PF17757: UvrB_inter" amino acids 313 to 402 (90 residues), 113.4 bits, see alignment E=1.3e-36 PF00271: Helicase_C" amino acids 592 to 698 (107 residues), 67.9 bits, see alignment E=2.7e-22 PF12344: UvrB" amino acids 705 to 746 (42 residues), 77.4 bits, see alignment (E = 1.8e-25) PF02151: UVR" amino acids 786 to 817 (32 residues), 37.8 bits, see alignment (E = 3.5e-13)

Best Hits

KEGG orthology group: K03702, excinuclease ABC subunit B (inferred from 90% identity to ara:Arad_2754)

Predicted SEED Role

"Excinuclease ABC subunit B" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92P88 at UniProt or InterPro

Protein Sequence (985 amino acids)

>SMc04231 excinuclease ABC subunit B (Sinorhizobium meliloti 1021)
MARSTKNSPKKSSAPGGFEEAPQAPLSGTPLSGNVSDWVKQLESEAEASTFESRREVASK
AGRHRKKVEISASKSARGTSMGGTTDPKTRAAAGLNPVAGLDVALEDADKLTSGSGVTAT
VEALAKLIESGNPLFKDGKLWTPHRPARPEKSEGGIAIRMQSDYEPAGDQPTAIADLVDG
LTSGERNQVLLGVTGSGKTFTMAKVIEATQRPAVILAPNKTLAAQLYSEFKNFFPDNAVE
YFVSYYDYYQPEAYVPRSDTYIEKESSINEQIDRMRHSATRSLLERDDVIIVASVSCIYG
IGSVETYTAMTFQMSVGDRLDQRQLLADLVAQQYKRRDMDFQRGSFRVRGDTIEIFPAHL
EDAAWRISMFGDEIDSITEFDPLTGQKTGDLKSVKIYANSHYVTPRPTLNAAIKAIKEEM
SQRLAELERAGRLLEAQRLEQRTRYDIEMLEATGSCQGIENYSRYLTGRRPGEPPPTLFE
YIPDNALIFIDESHVTIPQIGGMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRP
DTIAVSATPGAWEMEQAGGVFAEQVIRPTGLIDPPVEVRSAKTQVDDVLGEIRETAAAGY
RTLVTVLTKRMAEDLTEYLHEQGVRVRYMHSDIDTLERIEIIRDLRLGAFDVLVGINLLR
EGLDIPECGFVAILDADKEGFLRSETSLIQTIGRAARNVDGKVILYADTITGSMQRAMEE
TSRRREKQMAYNAEHGITPESVKAKISDILDSVYERDHVRADISGVAGKGFADGGHLVGN
NLQAHLNALEKQMRDAAADLDFEKAARLRDEIKRLKAAELAVLDDPMAREEAKSQESSKR
ASKGVPGTTDSLPLVGSVGEAKSDGEGKTQSYFQKPSLDNMGPGTDTERPLFRKPELDEM
GRDVAIPSSRGREEGARKADEGQSLFRKNTLDEMTVGRTEKPVPGQAPEKPTLTRAKPGV
GSYEDPAEEKRRKSRTKGKTGRPGR