Protein Info for SMc04219 in Sinorhizobium meliloti 1021

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF00005: ABC_tran" amino acids 21 to 163 (143 residues), 119 bits, see alignment E=3.7e-38 PF13304: AAA_21" amino acids 131 to 192 (62 residues), 34.4 bits, see alignment E=3.6e-12

Best Hits

KEGG orthology group: K09687, antibiotic transport system ATP-binding protein (inferred from 100% identity to sme:SMc04219)

Predicted SEED Role

"ABC-type multidrug transport system, ATPase component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92P94 at UniProt or InterPro

Protein Sequence (308 amino acids)

>SMc04219 ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MAPIVSVSNLSKTYASGFQALKGVSLDIEEGEILALLGPNGAGKTTLISIVCGIVNATGG
KVTVGGNDVVRDFRQTRAMIGLVPQELTTDAFETVWNTVSFSRGLHGKKPDPAHIEKVLK
DLSLWNKKDSTLRELSGGMKRRVLIAKALSHEPRVLFLDEPTAGVDVSLRKSMWEVVQRL
RASGVTIILTTHYIEEAEEIADRIAVINSGEILLVEDKNALMTKLGRKQLRVDLAQPLER
VPDSLASYNLLLEGEGERLIYEYDTSADRTGITSLLAALAEAGIRLRDISTRQSSLEDIF
VEIVEAGR