Protein Info for SMc04119 in Sinorhizobium meliloti 1021

Annotation: phosphopentomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01696: phosphopentomutase
  • amino acids 3 to 402 (400 residues), 491.4 bits, E=8.3e-152
• PF01676: Metalloenzyme
  • amino acids 3 to 396 (394 residues), 154.7 bits, E=1.6e-49

Best Hits

Swiss-Prot: 100% identical to DEOB_RHIME: Phosphopentomutase (deoB) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K01839, phosphopentomutase [EC: 5.4.2.7] (inferred from 100% identity to smk:Sinme_3464)

MetaCyc: 57% identical to phosphopentomutase (Escherichia coli K-12 substr. MG1655)
Phosphopentomutase. [EC: 5.4.2.7]; 5.4.2.7 [EC: 5.4.2.7]

Predicted SEED Role

"Phosphopentomutase (EC 5.4.2.7)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 5.4.2.7)

MetaCyc Pathways

• purine ribonucleosides degradation (6/6 steps found)
• superpathway of purine deoxyribonucleosides degradation (6/7 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (5/6 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (2/3 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway
• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.7

Sequence Analysis Tools

See Q92T47 at UniProt or InterPro

Protein Sequence (406 amino acids)

>SMc04119 phosphopentomutase (Sinorhizobium meliloti 1021)
MARAFLFVLDSFGIGNAPDAEAFGDLGADTLGHIAEFCAAGAADRAGLREGPLHLPNMSA
LGLMHAARLATGRLPAGMALPERVYGIYGAASEVSRGKDTPSGHWEIAGTPVTFDWGYFP
AEGDAFPPELVEAICREGDVPGILGNCHASGTDIIARHGEEHMRSGKPICYTSSDSVFQI
AAHEQTFGLERLLNLCEVVRRLVDDYNIGRVIARPFVGSDPGSFTRTGNRRDYSVLPPEP
TVLDRLQEAGRTVHAIGKIGDIFAHQGVTRLTKANGNMALFDASLEAIEEAEDGALVFTN
FVDFDMLYGHRRDVSGYAAALEAFDARLPDLDRRLKPGDMVILTADHGCDPTWRGTDHTR
ERVPVLMFGPTLRSRSFGIADSFAHIGETVARHLGIGVGPHGRSLI