Protein Info for SMc04112 in Sinorhizobium meliloti 1021

Annotation: pilus assembly signal peptide protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR03177: Flp pilus assembly protein CpaB" amino acids 6 to 236 (231 residues), 214 bits, see alignment E=1.1e-67 PF08666: SAF" amino acids 46 to 112 (67 residues), 32.5 bits, see alignment E=1e-11 PF16976: RcpC" amino acids 120 to 224 (105 residues), 96.7 bits, see alignment E=8.3e-32

Best Hits

KEGG orthology group: K02279, pilus assembly protein CpaB (inferred from 100% identity to sme:SMc04112)

Predicted SEED Role

"Flp pilus assembly protein RcpC/CpaB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92T42 at UniProt or InterPro

Protein Sequence (269 amino acids)

>SMc04112 pilus assembly signal peptide protein (Sinorhizobium meliloti 1021)
MRPVRIIILAVAIGSAAMAGLLAMKLTRAPAPQTAEPVIEQAPTINVLVAGKSLPVGSRL
GADSIHWKAWPKDGVAEGMITEENRPAAVEDLAGAVVRLPIFTGEPVRQEKIADASNRIM
SSLLPAGKRAVATEITVATGAGGFILPNDRVDVIMVRKSDGDLYLTETVLSNVRVLAIDQ
QIEEKEDGSKAVVGTTATLELTPDQSKVMTVAQQMADRISLALRSVADAQEPDTTAADYL
LNGDGRPSIQVIKSGSIVKGDGVALQNQK