Protein Info for SMc04109 in Sinorhizobium meliloti 1021
Annotation: response regulator protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: K02282, pilus assembly protein CpaE (inferred from 100% identity to sme:SMc04109)Predicted SEED Role
"Type II/IV secretion system ATPase TadZ/CpaE, associated with Flp pilus assembly" in subsystem Widespread colonization island
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q92T40 at UniProt or InterPro
Protein Sequence (428 amino acids)
>SMc04109 response regulator protein (Sinorhizobium meliloti 1021) MNAIEYTIDSGGTGDWPADGTRPGDLEQLRPLPRISIHAFCESEAVQRLMERCGQDRRMA KVSLRVTGGGIAAAANTFAGASTPNLIILETATEPGALLSELAPLAEVCDPSTRVIVIGR HNDIALYRELIRNGISEYMVAPVGMADMLSAVSAIFVDPEAEPLGRSLAFIGAKGGCGSS VIAHNCAWGISNLFSTETILADLDLPYGTANIDFDQDPPQGIAEAVFAPERLDEVFLDRL LTRCSEHLSLLAAPSMLDRAYDFETGAFQPILEILQRSAPVSVLDLPHGWTDWTRSVLSA ADEVVITAAPDLASLRNAKNLLDALKKLRPNDKVPHLVLNQVGVPKRPEIAPDEFCASLE IEAAAIIPFDAVLFGNASNSGRMIAEIDRKSPAAETFAQLSHLLTGRTAIKKARRGGLGK VLAKLGRR