Protein Info for SMc04037 in Sinorhizobium meliloti 1021

Annotation: peptide ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00496: SBP_bac_5" amino acids 71 to 420 (350 residues), 337.3 bits, see alignment E=6.4e-105

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 100% identity to sme:SMc04037)

Predicted SEED Role

"Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2); Putative hemin-binding lipoprotein" (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92M36 at UniProt or InterPro

Protein Sequence (504 amino acids)

>SMc04037 peptide ABC transporter (Sinorhizobium meliloti 1021)
MTKRWNKIGRAAFAAALMLSAGYAEAAGILSIGRREDSTTFDPIKSAQNVDNWVFSNVFD
VLVRVDKTGTKLEPGLAESWTLSDDGLTYTFKIRDAKFSDGSPITAEDAAFSLLRIRDHE
GSLWSDSYKIIETAEAADPKTLVVKLKTPSAPFLSTLALPNVSVLSKKAVEAGEDAFAEL
PTASSGAFTVKEWRRGDRVILEKNPNFWQADRVKLDGVEWISVPDDNTRMLNVQAGQLDT
AIFVPFSRVEELKKDPNLTVHIDTSTREDHLLINHEHGMLAKKEVRQALDMAIDKKAIVD
TVTFGIGTVANSYIPKGSLYHYDANYQYPYDPEKAKAMLAEAGASDLTLNYVVNAGNEVD
EQIAVLLQQQFAKAGVTVNLQKVDASQSWDMLVAGDYDISVMYWTNDVLDPDQKTTFVLG
HDTNMNYMTRYNSEKVKELVAAARLELDPAKREAMYVDIQKTAKDDVHWIDLYYSPYLNV
SRKNIENFYQNPLGRFFLEDTVKN