Protein Info for SMc04011 in Sinorhizobium meliloti 1021

Annotation: sigma-54-dependent transcription regulator protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 513 PF00072: Response_reg" amino acids 5 to 113 (109 residues), 93.4 bits, see alignment E=2.6e-30 PF00158: Sigma54_activat" amino acids 145 to 311 (167 residues), 231.4 bits, see alignment E=1.3e-72 PF14532: Sigma54_activ_2" amino acids 148 to 316 (169 residues), 66.9 bits, see alignment E=5.6e-22 PF07728: AAA_5" amino acids 169 to 287 (119 residues), 29 bits, see alignment E=2.5e-10 PF02954: HTH_8" amino acids 461 to 501 (41 residues), 45.5 bits, see alignment 1.2e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMc04011)

Predicted SEED Role

"Response regulatory protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92M58 at UniProt or InterPro

Protein Sequence (513 amino acids)

>SMc04011 sigma-54-dependent transcription regulator protein (Sinorhizobium meliloti 1021)
MTSHILVIDDDPVQRRLLTNMIERLGHVAHLADNGRSGLELLQRKGGIINVILLDLLMPE
MNGHGLLEALAERGIDIPVIVQTGQGGIETVVQAMQAGAFDFLVKPVSPERLSIALGNAL
KMASRDGKVKTARRPRGGAVGFDDIVSASPAMIRVIDLARRAAQSNIPIVLEGESGVGKE
MVARAIQAASDRAAKPFVTVNCGAIPHNLVESILFGHEKGAFTGASEKHSGKFVDADGGT
LFLDEIGDLPLDVQVKLLRAVQQGEIETIGARQPQKVNVRLISATNKDLITEVREGRFRE
DLYYRLNVFPITIPALRRRKEDIPVLVRAFVERFSAEQRLDQRLTVSSGAMALLTSYDWP
GNIRQLENAIFRAVVLADGHELTVRDFPQVATQIPGYIVADRSGLSWGEAGPERRPASGQ
LAAAQADAGAREQPAHSEQTPEGRLENAIASLSEGGEVRKLAEVEEELIRFALKFYRGQM
SQVARKLGIGRSTLYRKLKDYGIDPDNPLREAA