Protein Info for SMc03942 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 773 transmembrane" amino acids 26 to 44 (19 residues), see Phobius details amino acids 50 to 67 (18 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 144 to 161 (18 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details PF12860: PAS_7" amino acids 222 to 335 (114 residues), 52.3 bits, see alignment E=1.2e-17 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 342 to 498 (157 residues), 87.2 bits, see alignment E=5.2e-29 PF00990: GGDEF" amino acids 343 to 495 (153 residues), 108.3 bits, see alignment E=6.8e-35 PF00563: EAL" amino acids 519 to 750 (232 residues), 218.3 bits, see alignment E=2.1e-68

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_2918)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92JW6 at UniProt or InterPro

Protein Sequence (773 amino acids)

>SMc03942 hypothetical protein (Sinorhizobium meliloti 1021)
MTRNERGALPADIYLSFVSSLYQNRGTLVIGMLSHVVTFLLVFLKTSDTLYLGCTVAIVV
LWIVRNLDMMRFDQLDLSGADYAAIRMWENRYIVGGVAVTLTCGIACGYAIAVTRDVFSQ
VACVSVTLASMISLVGRNYGSERAVLLLSSSACLPMMIGALSLGDPFMAVLAVLIVPFIL
TTWMMANNVRGYLFEKILAARDENVLAALETKTIAGQFDAALNNMTHGLFMLDDRHRIVV
ANERACELLHLGDKAQLKGWLLGDVLERGSDALALDPERSDSIARQLDLLIEGKRSRALV
TISEELLLEFSANRRENGEIVLIFEDVTARVQAERQVLQMVRFDTLTGLPSRDYFAELTH
NAVAAGTAHDRDIGLLLVDIAEFKHVNDTRGHVAGDKLLQAIADRLKGLAGSEAIAARLM
GDEFVVFFHNRVGRSGLEERIRAVHAKLHGTYMADGFTFNMAMNAGFVIVRKSEFRLEEL
QIKADLALSEAKARNNGGCTAFEAEMEGRYLDRQKLKSDLREAIGRGDLSLAYQPMFTPD
GSRVVSCEALARWTHPERGPVPPDIFIQLAEEMGLVTDITRFVVRHACRDCLTWPAEVAV
SVNLSVLDLHGDEIVAIVAEALAESGLNPARLHLEVTESCLMDEPVKVQAVLRELRERGM
AIAIDDFGTGYSSLSYLDALPVSIIKVDRSFVRDIHVNSRRFKLLLGTVNLARALELKAV
VEGVETAEQLQLINEHNCADLIQGFVFAAPMPASAVAVLCGHGMPEPVAERTA