Protein Info for SMc03871 in Sinorhizobium meliloti 1021

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 TIGR01277: thiamine ABC transporter, ATP-binding protein" amino acids 8 to 214 (207 residues), 249.4 bits, see alignment E=1.4e-78 PF00005: ABC_tran" amino acids 25 to 162 (138 residues), 112.5 bits, see alignment E=2.5e-36

Best Hits

Swiss-Prot: 100% identical to THIQ_RHIME: Thiamine import ATP-binding protein ThiQ (thiQ) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K02062, thiamine transport system ATP-binding protein (inferred from 100% identity to sme:SMc03871)

MetaCyc: 47% identical to thiamine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-32-RXN [EC: 7.6.2.15]

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92L31 at UniProt or InterPro

Protein Sequence (238 amino acids)

>SMc03871 ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MSSTALAVKGVEISFETTTLAFDCAVPAKRIVAVAGASGSGKSTLFNIIAGFEQPGRGEV
RILGEEMTGRAPAERPVSIIFQEHNLFAHLDVATNVGFGISPALRLDAANRTKVEDALAR
VGLAGFGKRLPPTLSGGERQRVALARAFVRHRPILLLDEPFAALDPGMRAEMRALISDLH
EEEGNTILMITHHPDDVRALADSVLFLDRGRIVAHDEVDRFLGRRDIAAINRFLGNEG