Protein Info for SMc03825 in Sinorhizobium meliloti 1021

Annotation: transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 50 to 70 (21 residues), see Phobius details amino acids 78 to 97 (20 residues), see Phobius details amino acids 104 to 122 (19 residues), see Phobius details amino acids 134 to 159 (26 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 217 to 238 (22 residues), see Phobius details amino acids 250 to 270 (21 residues), see Phobius details amino acids 278 to 299 (22 residues), see Phobius details amino acids 307 to 328 (22 residues), see Phobius details amino acids 340 to 362 (23 residues), see Phobius details amino acids 368 to 388 (21 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 15 to 363 (349 residues), 214.7 bits, see alignment E=1.5e-67 PF07690: MFS_1" amino acids 16 to 356 (341 residues), 138.8 bits, see alignment E=2.2e-44 PF00083: Sugar_tr" amino acids 37 to 186 (150 residues), 26.3 bits, see alignment E=3.5e-10

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 100% identity to sme:SMc03825)

Predicted SEED Role

"Nucleoside ABC transporter, permease protein 1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92L74 at UniProt or InterPro

Protein Sequence (412 amino acids)

>SMc03825 transporter (Sinorhizobium meliloti 1021)
MTLRMSERRTSIIGAFLVALGPISMALYTPAMPELVRAFASSEAAIKMTLSLYFGGFAFA
QLVSGTLSDVIGRRRTTLIFMAIYLAGSLMAAFAPSIPVLLAGRLVQGIGASVGMTVARA
IVRDQFTGTTAARIMNMIGMMLALGPAVSPTLGSIALGLFGWQSIFLLMVGFALMACFIV
QLFMAETTTPDRSKGHFRPILAAYGELMRDGRFVSSTLVIAGAVGALYAWATMLPFVLIS
QVGLTPTEFGIGMLMQSGLFFSGTVTMRLMMRRFTPQALVPAGLFFIGAASLALAFTMHA
LEPTFLSVMTPIGIYAFGIAFVMPYMMTAAMAPFPHIAGTASAMMGFIQMSAGLLGGALA
ALVGVPAMALGTIIPSFGLLSLASYFWYRRTVRLRPLVAPAAAETPLSEAAE