Protein Info for SMc03783 in Sinorhizobium meliloti 1021

Annotation: carboxy-terminal processing protease precursor signal peptide protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR00225: C-terminal processing peptidase" amino acids 52 to 368 (317 residues), 338.9 bits, see alignment E=1.5e-105 PF00595: PDZ" amino acids 97 to 167 (71 residues), 41 bits, see alignment E=4.2e-14 PF13180: PDZ_2" amino acids 99 to 178 (80 residues), 51.7 bits, see alignment E=1.8e-17 PF17820: PDZ_6" amino acids 114 to 168 (55 residues), 44.1 bits, see alignment 2.9e-15 PF03572: Peptidase_S41" amino acids 196 to 363 (168 residues), 192.6 bits, see alignment E=7.7e-61

Best Hits

Swiss-Prot: 66% identical to CTPA_BARBK: Carboxy-terminal-processing protease (ctpA) from Bartonella bacilliformis (strain ATCC 35685 / NCTC 12138 / KC583)

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 100% identity to sme:SMc03783)

Predicted SEED Role

"Carboxyl-terminal protease (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q926B9 at UniProt or InterPro

Protein Sequence (440 amino acids)

>SMc03783 carboxy-terminal processing protease precursor signal peptide protein (Sinorhizobium meliloti 1021)
MIRRASLVLVGALMGATAMGVVYSATMPAVAANSSTYRELAIFGDVFERVRAQYVTPPQD
DKLIENAINGMLTSLDPHSSYMNSTDAEDMRTQTRGEFGGLGIEVTMEEDLVKVTSPIDD
TPAARAGVLAGDFISKIDGQDVRGLKLEEAVDKMRGAVGTPIKLTILRKGAEKPIELTIV
RDVIAVRAVKVRVEGDVGYLRVISFTEKTFEDLKKGIEKIQAEVPADKLKGYVLDLRLNP
GGLLDQAINVSDAFLERGEVVSTRGRNPDETRRFNATPGDLAGGKPVVVLVNGGSASASE
IVAGALQDLKRATVLGTRSFGKGSVQTIIPLGDAGALRLTTALYYTPSGKSIQGTGITPD
IKVEQPLPPELLGKVEAQGESDLRGHIPGQEETEEGSGSVAYVPPETKDDIQLNYAFDLL
RGKKTDPSFPANPEQAQLKE