Protein Info for SMc03775 in Sinorhizobium meliloti 1021

Annotation: GTPase ObgE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 TIGR02729: Obg family GTPase CgtA" amino acids 43 to 365 (323 residues), 444.3 bits, see alignment E=1.2e-137 PF01018: GTP1_OBG" amino acids 45 to 198 (154 residues), 201.4 bits, see alignment E=1e-63 PF01926: MMR_HSR1" amino acids 202 to 318 (117 residues), 85.8 bits, see alignment E=3.6e-28 PF02421: FeoB_N" amino acids 203 to 360 (158 residues), 49.6 bits, see alignment E=5.1e-17

Best Hits

Swiss-Prot: 100% identical to OBG_RHIME: GTPase Obg (obg) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03979, GTP-binding protein (inferred from 100% identity to sme:SMc03775)

Predicted SEED Role

"GTP-binding protein Obg"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92LB4 at UniProt or InterPro

Protein Sequence (376 amino acids)

>SMc03775 GTPase ObgE (Sinorhizobium meliloti 1021)
MTSAGSAYIDGAKAERDRERARAAPHSVLNLKRSRRNGEPMKFLDETKVYIRSGDGGAGA
VSFRREKFIEFGGPDGGDGGRGGDVWVEAVNGLNTLIDFRYQQHFKAKTGTHGMGRNRTG
AKGGDVTLKVPVGTQIFEEDNETLIVDMVAEGQRYRLAAGGNGGFGNAHFKSSTNQAPSW
ANPGLEGEEKTIWLRLKLIADAGLVGLPNAGKSTFLAACTRARPKIANYPFTTLHPNLGV
ATIDEKEFIIADIPGLIEGAHEGVGIGDRFLGHVERTRVLLHLVSAQEEDVAKAYKTVKH
ELEAYGGGLEEKPQIVALSQIDVLDEEELKAKAKALGKACGTPPLLISAVTNKGMTEALR
ALRSVIAAAKAGEEEA