Protein Info for SMc03298 in Sinorhizobium meliloti 1021

Annotation: transposase number 3 for insertion sequence ISRM26

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 PF13007: LZ_Tnp_IS66" amino acids 55 to 127 (73 residues), 49.2 bits, see alignment E=1.5e-16 PF13005: zf-IS66" amino acids 137 to 172 (36 residues), 36.3 bits, see alignment 1.2e-12 PF03050: DDE_Tnp_IS66" amino acids 192 to 484 (293 residues), 328.9 bits, see alignment E=5.9e-102 PF13817: DDE_Tnp_IS66_C" amino acids 491 to 529 (39 residues), 61.1 bits, see alignment 1.8e-20

Best Hits

Swiss-Prot: 90% identical to Y4QI_SINFN: Uncharacterized protein y4qI (NGR_a01890) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K07484, transposase (inferred from 100% identity to sme:SMc03298)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92LC7 at UniProt or InterPro

Protein Sequence (537 amino acids)

>SMc03298 transposase number 3 for insertion sequence ISRM26 (Sinorhizobium meliloti 1021)
MDLPLSDLPDDVDALKAMVLALAREQAAKEVRLKVAEIARLEAVEKSANERIANLTLIMK
VLQRTQNGKRSERLRLGVNDEQVSFAFEEVETGLSAIRSELDRAAKDKPKRAPRPRKGFA
AHLERIEEVIEPEIPAGCEGLAKVLIGEDRSERLDVVPPKFRVIVTRRPKYAFRGSDGVV
QALAPAHIIEGGLPTERLLAYIAVSKYADGLPLYRQEAIYLRDGVEISRSLMAQWMGHLG
FELQMLADYILERVKEGERIFADETTLPTLAPGSGKTTKAWLWAYARDDRPYGGTSPPMV
AYRFEDSRGADCVTRHLSGFTGILQVDGYSAYTNLAKTRAKTGSNETVQLAGCWAHLRRK
FYDLHISGVSQAATDTVLAMTELWRIEDEVRGKDADSRAARRQEKSSTTAASLFELWEKE
LGKVSGKSKTAEAIRYALTRREALERFLTDGRIEIDSNIVERAIRPQTITRKNSLFAGSE
GGGRTWAAVATLLQTCKMNGVDPLDWLSQTLTRIAQGWPASEIEALMPWNFRSDAVS