Protein Info for SMc03242 in Sinorhizobium meliloti 1021

Annotation: GTP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 608 TIGR00231: small GTP-binding protein domain" amino acids 1 to 138 (138 residues), 86.8 bits, see alignment E=1.4e-28 PF00009: GTP_EFTU" amino acids 2 to 194 (193 residues), 200.9 bits, see alignment E=3.7e-63 TIGR01394: GTP-binding protein TypA/BipA" amino acids 3 to 598 (596 residues), 919.1 bits, see alignment E=1e-280 PF01926: MMR_HSR1" amino acids 6 to 127 (122 residues), 22.6 bits, see alignment E=2.5e-08 PF03144: GTP_EFTU_D2" amino acids 217 to 288 (72 residues), 53 bits, see alignment E=9.7e-18 PF00679: EFG_C" amino acids 395 to 479 (85 residues), 77.8 bits, see alignment E=1.4e-25 PF21018: BipA_C" amino acids 484 to 592 (109 residues), 156.4 bits, see alignment E=5.2e-50

Best Hits

Swiss-Prot: 51% identical to TYPA_BACSU: GTP-binding protein TypA/BipA homolog (typA) from Bacillus subtilis (strain 168)

KEGG orthology group: K06207, GTP-binding protein (inferred from 100% identity to smk:Sinme_3144)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92LG8 at UniProt or InterPro

Protein Sequence (608 amino acids)

>SMc03242 GTP-binding protein (Sinorhizobium meliloti 1021)
MSIRNIAIIAHVDHGKTTLVDELLKQSGSFRENQRVAERMMDSNELEKERGITILAKATS
VEWKGTRINIVDTPGHADFGGEVERILSMVDGAIVLVDAAEGPMPQTKFVVGKALKVGLR
PIVAINKIDRPDARHEEVINEVFDLFAALDATDEQLDFPILYGSGRNGWMNVAPEGPQDQ
GLAPLLDLVLDHVPEPSVGEGPFRMIGTILEANPFLGRIITGRIHSGSIKPNQAVKVLGQ
DGKVLESGRISKILAFRGIERQPIEEAHAGDIVAIAGLSKGTVADTFCDPAINEPLKAQP
IDPPTVTMSFLVNDSPLAGTEGDKVTSRVIRDRLFKEAEGNVALKIEESSEKDSFYVSGR
GELQLAVLIETMRREGFELAVSRPRVVMHKDENGQLLEPIEEVVIDVDEEHSGVVVQKMS
ERKAEMAELRPSGGNRVRLVFFAPTRGLIGYQSELLTDTRGTAIMNRLFHDYQPYKGEIG
GRVNGVLLSNDAGESVAYAMFNLEDRGPMIIDAGEKVYAGMIIGIHTRDNDLEVNVLKGK
KLTNMRASGKDEAVKLTPPIRMTLDRALSWIQDDELVEVTPKSIRLRKMYLDPNERKRFE
KSRTAGAA