Protein Info for SMc03127 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 132 to 158 (27 residues), see Phobius details amino acids 169 to 189 (21 residues), see Phobius details amino acids 225 to 251 (27 residues), see Phobius details amino acids 271 to 295 (25 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 1 to 101 (101 residues), 49.5 bits, see alignment E=4.6e-17 PF00528: BPD_transp_1" amino acids 112 to 303 (192 residues), 142.8 bits, see alignment E=1e-45

Best Hits

Swiss-Prot: 39% identical to GSIC_SHIDS: Glutathione transport system permease protein GsiC (gsiC) from Shigella dysenteriae serotype 1 (strain Sd197)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 100% identity to smk:Sinme_3021)

MetaCyc: 39% identical to glutathione ABC transporter membrane subunit GsiC (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"cell processes; transport of small molecules; amino acids, amines, peptides"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92LR4 at UniProt or InterPro

Protein Sequence (308 amino acids)

>SMc03127 ABC transporter permease (Sinorhizobium meliloti 1021)
MIRFVLVRLMRAVITILAVVTFAFVVLRMSGDPAQVMLGPDVPQDAVDAFRKTWGLDQPI
WIQYLAYIKSIFTGDFGVSMRDKASALHLVLERVPATLQLTLPALILKLMIGIPAGVYAA
LHRQSFADRGVITLAIIGFTVPSFVMGLVLVLIFSVLLGVLPSGGQDTWMHGILPTITMS
IGGIGILARFSRSAMIEVLGQPYIRTASAKGLKWRDVIWSHALPNAAVPIVTIVGFMVGS
LIAGAVVVESIFSWPGIGRLLIVSVSNRDLAVVQCILLIIAAAMVMSNLVVDLLYGWLDP
RLRSHAGH