Protein Info for SMc03063 in Sinorhizobium meliloti 1021

Updated annotation (from data): ABC transporter for D-maltose/D-trehalose/sucrose, permease component 2 (AglG)
Rationale: Specific phenotype on D-Maltose monohydrate; D-Trehalose dihydrate. Also mildly important for D-cellobiose utilization, which has its own ABC transporter, so the cause is unclear. Also reported to transport sucrose (PMID:10400573, PMID:12003938)
Original annotation: alpha-glucoside ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 173 to 194 (22 residues), see Phobius details amino acids 201 to 223 (23 residues), see Phobius details amino acids 241 to 263 (23 residues), see Phobius details amino acids 284 to 307 (24 residues), see Phobius details amino acids 345 to 364 (20 residues), see Phobius details PF00528: BPD_transp_1" amino acids 182 to 371 (190 residues), 49.7 bits, see alignment E=2e-17

Best Hits

Swiss-Prot: 100% identical to AGLG_RHIME: Alpha-glucoside transport system permease protein AglG (aglG) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K10234, alpha-glucoside transport system permease protein (inferred from 100% identity to smk:Sinme_0391)

Predicted SEED Role

"Alpha-glucoside transport system permease protein AglG"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q9Z3R7 at UniProt or InterPro

Protein Sequence (380 amino acids)

>SMc03063 ABC transporter for D-maltose/D-trehalose/sucrose, permease component 2 (AglG) (Sinorhizobium meliloti 1021)
MNPSRRSPLTWAVHLSVLLLVLLWTLPTAGLLISSLRDKDQLAVSGWWTALSSSSRNAVV
RAPSAEDQVERDGKFVISGNLLEGRGEVSAFGFSSREPTKFKPGETAELNDGERLTVQSD
GSFEIVSDQRMEGSRGQRIFFTATTPPRFTLDNYAEVLSAAGIGRSFLNSLTVAVPSTVI
PILIAAFAAYALAWMPFPGRAVLLAVVVGLLVVPLQMSLIPLLQLYNGVGAFFGVSAKTY
MGIWLAHTGFGLPLAIYLLRNYMAGLPREIMESARVDGASDFDIFVKIILPLSFPALASF
AIFQFLWTWNDLLVAIVFLGAGDDKLVLTGRLVNLLGSRGGNWEILTASAFITIVVPLIV
FFALQRYLVRGLLAGSVKGG