Protein Info for SMc02863 in Sinorhizobium meliloti 1021

Annotation: recombination protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 PF02463: SMC_N" amino acids 6 to 357 (352 residues), 69 bits, see alignment E=4.3e-23 TIGR00611: DNA replication and repair protein RecF" amino acids 6 to 356 (351 residues), 185 bits, see alignment E=1.2e-58 PF13304: AAA_21" amino acids 31 to 338 (308 residues), 33 bits, see alignment E=7.2e-12

Best Hits

Swiss-Prot: 100% identical to RECF_RHIME: DNA replication and repair protein RecF (recF) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03629, DNA replication and repair protein RecF (inferred from 100% identity to sme:SMc02863)

Predicted SEED Role

"DNA recombination and repair protein RecF" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P56903 at UniProt or InterPro

Protein Sequence (374 amino acids)

>SMc02863 recombination protein F (Sinorhizobium meliloti 1021)
MPHKVFLTRLKLSDFRNYATLALDLDQRHVVLTGENGAGKTNLMEGVSFLSPGRGLRRAA
YADVARVGAPDGFSVFAAVDGMEGSVEIGTGTQGTEEGQSRRLRINGTAARTVDELTDHL
RVLWLTPAMDGLFTGPSADRRRFLDRLVLSLDPEHGRRASEFDRAMRSRNRLLSEFRPDP
AWLSAIEREMAGLGISMALARQEMLGLLSALVERSRSDGTFPSASLSLAGFLDDCAGIPA
FELEERYLAMLAEGRARDAAAGRTLDGPHRSDLLIRHREKDIEAERCSTGEQKALLVGLV
LAHARLVGDMTGHAPVLLLDEIAAHLDQGRRAALFDLVDGLGGQSFMTGTDRAMFDALGE
RAQYLAVANGRVSG