Protein Info for SMc02825 in Sinorhizobium meliloti 1021

Annotation: aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 PF21337: Peptidase_M17_N_1" amino acids 37 to 135 (99 residues), 59.6 bits, see alignment E=3.1e-20 PF00883: Peptidase_M17" amino acids 152 to 454 (303 residues), 352.6 bits, see alignment E=2e-109

Best Hits

KEGG orthology group: K01255, leucyl aminopeptidase [EC: 3.4.11.1] (inferred from 100% identity to smk:Sinme_3479)

Predicted SEED Role

"Peptidase B (EC 3.4.11.23)" (EC 3.4.11.23)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.1

Use Curated BLAST to search for 3.4.11.1 or 3.4.11.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92T36 at UniProt or InterPro

Protein Sequence (463 amino acids)

>SMc02825 aminopeptidase (Sinorhizobium meliloti 1021)
MAPFQFIERQSPFNTSNGKTLPIFAVTPAHIETGSIDPIALDWAKKAGFKAESGAVLLIP
SADGHLGGALFGLGANPSDEPFLTGKLARALPAGKWHIETAPLTANRLALGYGLGSYRFE
RYKSAKTDAPTLLIPADSDATDIKRQLAGVFLARDLINTPTNDMGPEALEAAFRALAAHY
KADVSVISGEALLTENFPLVHTVGRASAEAPRLLEMRWGRKGHRKVTLVGKGVCFDTGGL
DIKPAASMLLMKKDMGGAANVMGLALMIMDAKLKVDLRVIVPVVENSISANAFRPGDIYK
SRKGLTVQIDNTDAEGRLILADALAYADEEKTDLVVDMATLTGAARVALGPDLPPFFTDD
DDLARDLAEASLTVDDPVWRMPLYRGYDKDVSARIADLTNAPSGGMAGSITAALFLKRFV
TNAKSWVHFDIFGWAQSERPHSPIGGEAQAIRALYHHIGRIAG