Protein Info for SMc02813 in Sinorhizobium meliloti 1021

Annotation: aminoglycoside N3-acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 74% identical to AACC4_SALSP: Aminoglycoside N(3)-acetyltransferase IV (aacC4) from Salmonella sp.

KEGG orthology group: K00662, aminoglycoside N3'-acetyltransferase [EC: 2.3.1.81] (inferred from 100% identity to sme:SMc02813)

Predicted SEED Role

"PROBABLE AMINOGLYCOSIDE N3'-ACETYLTRANSFERASE PROTEIN( EC:2.3.1.81 )"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.81

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92NC1 at UniProt or InterPro

Protein Sequence (272 amino acids)

>SMc02813 aminoglycoside N3-acetyltransferase (Sinorhizobium meliloti 1021)
MTQQNEWRASEIVDQLIALGVKPGGVLLVHCSFRSVRPVEGGPPGVIAALRAAIGPEGTL
VMPSWSGLDDEPFDPAATPATPDLGIVADTFWRLENVTRSDHPFAFAATGPLAARITSDS
LPLPPHAPASPIGRIHELDGQVLLLGVEHDSDTTLHLAELIAKVPYGVPRHCTVLDNGKP
IRVDYRENDHCCQNFNLADAWLRREGLQREGQVGHAHARLIRSRDIVRIASDRLARDPLV
FLHPIEAGCEECDAARQSAGCAPRSTSGGGQF