Protein Info for SMc02508 in Sinorhizobium meliloti 1021

Annotation: iron transport ATP-binding ABC transporter protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 PF00005: ABC_tran" amino acids 38 to 185 (148 residues), 103.4 bits, see alignment E=1.6e-33

Best Hits

Swiss-Prot: 67% identical to YFEB_YERPE: Chelated iron transport system membrane protein YfeB (yfeB) from Yersinia pestis

KEGG orthology group: K11607, manganese/iron transport system ATP-binding protein (inferred from 100% identity to sme:SMc02508)

Predicted SEED Role

"Manganese ABC transporter, ATP-binding protein SitB" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92LL4 at UniProt or InterPro

Protein Sequence (311 amino acids)

>SMc02508 iron transport ATP-binding ABC transporter protein (Sinorhizobium meliloti 1021)
MNLQEKARAYPGAAPQEEDGGIRVSGATVTYRNGHRALRDASFEIPTGTIAALVGVNGSG
KSTLFKAIMGFVRLAKGDISILGLTVPQALRQNLVAYVPQAEEVDWNFPVLVEDVVMMGR
YGHMNMLRIPKKADHEAVETALARVGMSEFRKRQIGELSGGQKKRVFLARALAQNGRVIL
LDEPFTGVDVKTEDAIIRLLVALREEGRVMLVSTHNLGSVPEFCDRTILLKNTVLAYGPT
ETTFTRENLELAFGGVLRHFVLGGENLHDDADPRQLSVISDDERPLVMYGARDRMVAQPA
KPESESEADSE