Protein Info for SMc02417 in Sinorhizobium meliloti 1021

Annotation: peptide-binding periplasmic ABC transporter protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00496: SBP_bac_5" amino acids 64 to 427 (364 residues), 288.9 bits, see alignment E=3.1e-90

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 100% identity to smk:Sinme_2644)

Predicted SEED Role

"Putative gluthatione transporter,solute-binding component" in subsystem Utilization of glutathione as a sulphur source

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92MM0 at UniProt or InterPro

Protein Sequence (520 amino acids)

>SMc02417 peptide-binding periplasmic ABC transporter protein (Sinorhizobium meliloti 1021)
MMKKLGLAATMLMGLTLSGHAETLKWGAARDIYSLDPYSYGDSYTLSFLNHVYEGLVRYD
ANLKIEPALAESWETVSDTVWRFHLRKGVKFHDGAEFTADDVLASLKRVSDPVSPLRGNL
PAYKSSKKVDDHTIDIELSGPYPLLLNDLTNIHVFDAGWLKTNNSEKPTDVGAKIEGYAT
YHTNGTGPFKLESRVPDSKTVLVKNPDWWDKTSKSNVDRIEFTPITSAATRVAALLSGEV
NFTENAPSQDLPRLQAQPDLKVMERTDLRTVMVGFNRKPELANGSENKFNDLRVRQAFAH
ALDRDLIQQRVMRGKSRTAGAVVAPEIPGYAPELDTTLAFDPALSKKLLAEAGASDYPFT
LVCTTDAYVNEEELCQGLVNLLSRAGFKPQLDIAPTAAQAPKRTSGKSDVYLIGWATEPM
LDSYSILLQMIQTKTANAGVFNWGGWSYPEIDKLIVQASTEMDRTKRLALQSKALQMVKD
EIVMLPLHQQPMAWVMSNKIDKIVQLPDNKPRHWLTQFAE