Protein Info for SMc02281 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF02321: OEP" amino acids 77 to 254 (178 residues), 38.1 bits, see alignment E=7.5e-14 amino acids 279 to 459 (181 residues), 49.4 bits, see alignment E=2.4e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_0228)

Predicted SEED Role

"Copper tolerance protein" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92S44 at UniProt or InterPro

Protein Sequence (481 amino acids)

>SMc02281 hypothetical protein (Sinorhizobium meliloti 1021)
MMKARMKLAATLALPLVLGGCVTAGEYAVKNAGFSLVAATTAEAADKQTVWVQNQEQARS
VSERVKTLMAKKAIDVETAVQVALLNNKGLQAAYADLGESAADAWQATMLVNPTVGVGLT
GIGTPGLTAFRTVEGAIVSNILALVTRDRNIALADTEFRKAQLDAASRTLQLASETRRAW
INAVAAWETVGQLNQAQAAADAASELAEKLGESGAMTKGSQAREHVFYAELAGEGAKARL
EARLAKEELTRLMGLWGSDVKFQVPNRLASLPKGLMKRDQIEAEALRRRVDLQMAKLDLE
ATARSYNLTEATRYVTDLNLLAGFETERAKEDGDISSETTGRVDLEFAIPIFDSGKARMR
KAELAYMRAANLLAEKAVNVRSEARSAYQAYRANYDIARHYRNSVVPLRTKIEEQSLLTY
NGMITSTFELLADSREKVNSILLAINAKRDFWLAEADLAPAIYGGGASGETEVAAAAESG
N