Protein Info for SMc02254 in Sinorhizobium meliloti 1021

Annotation: quinol oxidase subunit II transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 transmembrane" amino acids 6 to 37 (32 residues), see Phobius details amino acids 58 to 77 (20 residues), see Phobius details amino acids 82 to 100 (19 residues), see Phobius details amino acids 112 to 137 (26 residues), see Phobius details amino acids 157 to 180 (24 residues), see Phobius details amino acids 192 to 212 (21 residues), see Phobius details amino acids 224 to 247 (24 residues), see Phobius details amino acids 259 to 278 (20 residues), see Phobius details amino acids 298 to 321 (24 residues), see Phobius details PF02322: Cyt_bd_oxida_II" amino acids 5 to 323 (319 residues), 350.8 bits, see alignment E=3.6e-109 TIGR00203: cytochrome d ubiquinol oxidase, subunit II" amino acids 5 to 214 (210 residues), 154.2 bits, see alignment E=2.9e-49

Best Hits

KEGG orthology group: K00426, cytochrome bd-I oxidase subunit II [EC: 1.10.3.-] (inferred from 100% identity to smk:Sinme_0201)

MetaCyc: 56% identical to cyanide insensitive ubiquinol oxidase subunit II (Pseudomonas putida KT2440)
RXN-6883 [EC: 1.10.3.11]

Predicted SEED Role

"putative Cytochrome bd2, subunit II" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 1.10.3.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92S68 at UniProt or InterPro

Protein Sequence (334 amino acids)

>SMc02254 quinol oxidase subunit II transmembrane protein (Sinorhizobium meliloti 1021)
MAIDLPLIWAAIIAFAVLAYVVLDGFDLGVGILFPFFPEKHDRDVMMNSVAPVWDGNETW
LVLGGGGLLAVFPLAYATILPALYAPIIAMLIGLIFRGVAFEYRWRTQRGEFLWNWAFAG
GSMLAAFAQGLALGALVQGIPVENRAYVGGWWDWLTPFSIATGLAIVIGYALLGATWLVM
KTRGELAERARGVALRTALATVAAMGIVSLWTPFLEPVYLERWFGWPTAIFSVIVPLLVL
GCLYLLLKGIRDRHDVQPFIAALGLFVLGYIGIGISFYPFMVPPSLTIWDAAAPDESLAF
LLVGALVLVPMILTYTAYAYWVFRGKVDPEEGYH