Protein Info for SMc02219 in Sinorhizobium meliloti 1021
Annotation: amino acid-binding periplasmic protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to sme:SMc02219)Predicted SEED Role
"ABC transporter, periplasmic amino acid-binding protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q92S93 at UniProt or InterPro
Protein Sequence (307 amino acids)
>SMc02219 amino acid-binding periplasmic protein (Sinorhizobium meliloti 1021) MVERQLPKLDVVGSIPITRSNSSFHRGAIALRILWIFVLSAVLAPGLALAQPKELPRLFD ARERIAKPDLSGLARLRFLTTVDFPPFNFIDQSGKLSGFHVDLAREICRELEIEAKCQIQ AVTYPELMPALEQGQGEAIAAGIAVTSELRQRFAFSRAFMQLPARFVVNTKAAGAIAGPA DLAGKPVGVVSGTTHEAMLKAFFPKLEAKGFPDRDALLSALRGGTVAAAFSDGMQLSFWV SGNLAGGCCAMLEGSYFSQRFLGEGLTIMNRKAEPALTQAIDHALLALSRSGRLEEIYLR YFPDGIY