Protein Info for SMc02136 in Sinorhizobium meliloti 1021

Annotation: Hsp33-like chaperonin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 PF01430: HSP33" amino acids 17 to 323 (307 residues), 243.5 bits, see alignment E=1.5e-76

Best Hits

KEGG orthology group: K04083, molecular chaperone Hsp33 (inferred from 100% identity to sme:SMc02136)

Predicted SEED Role

"Chaperone protein Hsp33"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92S98 at UniProt or InterPro

Protein Sequence (330 amino acids)

>SMc02136 Hsp33-like chaperonin (Sinorhizobium meliloti 1021)
MTETAPGLGEFDFAGDDQVVPFQVEGLDVRGRAVQLGPMLDAILERHNYPLPVARLVAET
VVLTVLLGTSLKFEGKLIVQTQGDGPVDLVVADFSTPDRVRAYARYDKEALADAEKSGRV
QPHELLGNGVLAFTIDQGAHTQRYQGIVALDGATLEEIAGAYFRQSEQIPTRVRLAVAEL
LDKDENGKPRHRWRAGGMVAQFLPDAPDRMRQADLPGGGGDEGDEDFFDEDDLWAEAKVM
VETIDTDELTDPTVGTERLLYRLFHERGVRVYEPQAVYDRCSCSREKIRDVLVGLGNEDI
EASVEDGLIKVTCEFCSTTYRFEASEVRPQ