Protein Info for SMc02050 in Sinorhizobium meliloti 1021

Annotation: trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 PF05697: Trigger_N" amino acids 1 to 151 (151 residues), 117.2 bits, see alignment E=1.2e-37 TIGR00115: trigger factor" amino acids 11 to 425 (415 residues), 433.7 bits, see alignment E=3.3e-134 PF00254: FKBP_C" amino acids 164 to 245 (82 residues), 71.7 bits, see alignment E=8.1e-24 PF05698: Trigger_C" amino acids 268 to 425 (158 residues), 147.1 bits, see alignment E=7.2e-47

Best Hits

Swiss-Prot: 100% identical to TIG_RHIME: Trigger factor (tig) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03545, trigger factor (inferred from 100% identity to smk:Sinme_1349)

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Q12 at UniProt or InterPro

Protein Sequence (491 amino acids)

>SMc02050 trigger factor (Sinorhizobium meliloti 1021)
MQVIETLAQGLKRELKVVIPADEMQARMNERLVEVKDRVRINGFRPGKVPVAHLKKVYGK
SIMADLVNEIVREKPTEILTSRGEKSATQPEIAMTEDEAEADKILNAQADFEFTVAYEII
PPIELKDASGIKVTREVVDVSEDEVNEQIQRIAESARTYESKKGKAANGDRVTVDYLGKV
DGEAFDGGKDEDAELVLGSNRFIPGFEEQLVGVKAGDEKTITVTFPADYPAANLAGKEAT
FDITVKDVAAAAPIEINDELATKLGLESVDKLKEIVRGQIESQFGSITRQKVKRQLLDQL
DELYQFDTPERLVDAEFENIWRQINTDLQQAGKTFADEDTTEEEARAEYRKLAERRVRLG
LVLSEIGEKAGVQVSDDEMQRSLFEQLRQFPGQEKEILEYFRNTPGAAASLRAPLFEEKV
VDHLLTEVSVTDKKVSKEELTADDEGDEKPAKKTASKKKAAAKAEAGEGEEAAAPKKKAP
AKKKAADESAE