Protein Info for SMc01990 in Sinorhizobium meliloti 1021

Annotation: ferredoxin reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 PF07992: Pyr_redox_2" amino acids 5 to 304 (300 residues), 220.5 bits, see alignment E=5.2e-69 PF00070: Pyr_redox" amino acids 147 to 227 (81 residues), 55 bits, see alignment E=1.4e-18 PF14759: Reductase_C" amino acids 323 to 406 (84 residues), 43.1 bits, see alignment E=7.6e-15

Best Hits

KEGG orthology group: K00529, ferredoxin--NAD+ reductase [EC: 1.18.1.3] (inferred from 100% identity to sme:SMc01990)

Predicted SEED Role

"Ferredoxin reductase" in subsystem Anaerobic respiratory reductases

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.18.1.3

Use Curated BLAST to search for 1.18.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92MT6 at UniProt or InterPro

Protein Sequence (409 amino acids)

>SMc01990 ferredoxin reductase (Sinorhizobium meliloti 1021)
MMPERIVIVGGGQAGGRVAQILAGSPANLDIALIGLEPHPPYNRPPLSKGVLLGKSELKD
CVIWPQGDATAGRVRFYPGRRAESLDIHARHVITDDGARLDYDKLVLATGSRVRRLSVPG
AECDGVFTLRTFDDAVAIARRFHRSKRLLVVGGGFVGLEIAAAARSRGLETVVVEATNRL
LSRIVPQEIGAALARYHEAAGVSFRVGSMVEKLVANRSGKLKSAVLSNGETVPCDLAVIG
VGVTANTELAKEAGLEVQVGIRTDSALRASADGVYACGDAVSFWHPLFERYVRVEAWQNA
EDHARVVASQLLGQDMVCDTVPFFWSDQYEWSMQIAGIPYFGSQLVTNTVEEAKILYHLD
ARGRLVAATGLGHDRLIGRKIAEARRLIKRRARPNPQMLKTGQIQLEDG