Protein Info for SMc01985 in Sinorhizobium meliloti 1021

Annotation: cytochrome-c oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00510: COX3
  • amino acids 42 to 240 (199 residues), 68.4 bits, E=4.9e-23

Best Hits

KEGG orthology group: K02276, cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 100% identity to smk:Sinme_2568)

Predicted SEED Role

"Alternative cytochrome c oxidase polypeptide CoxP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

• aerobic respiration I (cytochrome c) (3/4 steps found)
• arsenite to oxygen electron transfer (1/2 steps found)
• aerobic respiration II (cytochrome c) (yeast) (2/4 steps found)
• arsenite to oxygen electron transfer (via azurin) (1/3 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

See Q92MU0 at UniProt or InterPro

Protein Sequence (240 amino acids)

>SMc01985 cytochrome-c oxidase (Sinorhizobium meliloti 1021)
MSAPMKKPAAETLPRPAGLAGLASDWASDQRTFKDVSWGKAMMWIFLLSDTFVFGCFLLA
YMSARMSTSVPWPNPSEVFALEIGGTHMPLILIAIMTFVLISSSGTMAMAVNYGYRRDRR
KTAALMLLTALFGAAFVGMQAFEWSKLIAEGVRPWGNPWGAAQFGSTFFMITGFHGTHVT
FGVIFLLIVARKVWRGDFETERRGFFTSRKGRYEIVEITGLYWHFVDLVWVFIFAFFYLW