Protein Info for SMc01885 in Sinorhizobium meliloti 1021

Annotation: aminopeptidase P protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 PF01321: Creatinase_N" amino acids 17 to 138 (122 residues), 56.2 bits, see alignment E=1.1e-18 PF16189: Creatinase_N_2" amino acids 158 to 318 (161 residues), 128 bits, see alignment E=7.1e-41 PF00557: Peptidase_M24" amino acids 324 to 538 (215 residues), 162.6 bits, see alignment E=2.3e-51 PF16188: Peptidase_M24_C" amino acids 548 to 609 (62 residues), 79.2 bits, see alignment E=3.6e-26

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 100% identity to sme:SMc01885)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92NN4 at UniProt or InterPro

Protein Sequence (611 amino acids)

>SMc01885 aminopeptidase P protein (Sinorhizobium meliloti 1021)
MFQSFEVTSTPQFGKERTTALRAALATLGVDGFLVPRADEFQGEYVPRSSERLSWLTGFT
GSAGVALVTQREAIVFVDGRYVTQLKEQVDGSVFTGGDLIGEPPHVWLERHGPKGFRLGI
DPWLHTAAEVRRLEKALAAIGGSVVLLDHNPLDRLWTDRPATPLGPVTIQPVEHAGQLAK
DKIAEIAAGVAKAKAAAVVLTDPSSVAWTFNIRGSDVPHTPHPLARAIIHADGSAELFLD
KRKTGIEQEAYLTQLADIMAPASFDDRLAALASTGAAIMIDPDLAPFAIGELIRRKEGSV
VEAVDPARLPRACKNAAEIAGSTRAHLQDGAAMVEFLAWLDGREPGSVTEIGATRQLEAT
RAAVGERMQNPLKDVSFDTIAGAGSHAAIMHYRVTNETDRRIEAGTMFLIDSGAQYINGT
TDITRTVAIGAVPEEQKRFFTLVLKGMIAISTARFPKGSRGVDLDPLARIALWKAGADYA
HGTGHGVGSYLSVHEGPQRIARLATQELLPGMILSNEPGYYRPGAFGIRIENLVVVREPE
EIEGGDQPMLGFDTLTFCPIDRRLVLPALLTDDELDWLNAYHAETLEKLMPLLSGTETRD
WLASATEAIVR