Protein Info for SMc01628 in Sinorhizobium meliloti 1021

Annotation: periplasmic binding ABC transporter protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 transmembrane" amino acids 22 to 40 (19 residues), see Phobius details TIGR01409: Tat (twin-arginine translocation) pathway signal sequence" amino acids 17 to 49 (33 residues), 19.3 bits, see alignment (E = 5.5e-08) PF01547: SBP_bac_1" amino acids 73 to 379 (307 residues), 76.7 bits, see alignment E=1.6e-25

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 100% identity to sme:SMc01628)

Predicted SEED Role

"Predicted erythritol ABC transporter 1, substrate-binding component" in subsystem Erythritol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92NG5 at UniProt or InterPro

Protein Sequence (481 amino acids)

>SMc01628 periplasmic binding ABC transporter protein (Sinorhizobium meliloti 1021)
MYDKEKDLIGAFLRGEVDRRGLLKGLGAAGLTAGTAGTLFNMMSTQALAADFDWKAHSGK
SLKLLLNKHPYADAMIANLQAFKDLTGIEVTYDVFPEDVYFDKVTAALSSGSSEYDAFMT
GAYMTWTYGPAGWITDLNEWIKDPAKTNPQYGWDDFLPGVKASCAWNGQPGGALGSEDAK
QWCIPWGYEQNNLSYNQEMFEKVGASVPKNLDELVATAAKLNKDVGGGVYGIGVRGSRSW
ATIHPGFLSGYANFGQKDLNVSEDGKLSAAMNTAESKAFHAKWVQMIQESGPKDWSTYTW
YQVGTDLGAGASAMIYDADILGYFMNGGDNKMAGKLAYAPFAANPEAKAPTPNIWIWSLA
MSNFAKDKDATWYFLQWASGLEHAIFGATKMDFVNPVRASVWKDEIFRERLNKSYPGYVE
MHDVSAPGAKIHFTPQPLFFDLTTEWAATLQKMVAKEVPVDEGLDRLVESINRQLAEAGL
G