Protein Info for SMc01611 in Sinorhizobium meliloti 1021

Annotation: ferrichrome receptor precursor protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 733 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF07715: Plug" amino acids 76 to 180 (105 residues), 92.7 bits, see alignment E=2e-30 TIGR01783: TonB-dependent siderophore receptor" amino acids 78 to 730 (653 residues), 402.3 bits, see alignment E=2.2e-124 PF00593: TonB_dep_Rec_b-barrel" amino acids 273 to 702 (430 residues), 236.8 bits, see alignment E=9.5e-74

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to smk:Sinme_2203)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q926C7 at UniProt or InterPro

Protein Sequence (733 amino acids)

>SMc01611 ferrichrome receptor precursor protein (Sinorhizobium meliloti 1021)
MKCRIRGAHLKTLLASGVALAPLMMSGIALAQEGNATQLERIVVEGGNAAGASATGPVDG
YVAKATATGSKTAMPLNEIPQSVSVVGREELDDRAVVNKVDEALRYTPGVLSAPFGTDPD
TDWFYIRGFDAAQTGLFLDGLPLFSFGFGNFQVDPFMLERVEVLKGPASVLYGGSNPGGI
INLISKRPLDEPLYYTEVGINSNGNAFTGFDVNDKLNDDGTVRYRLTGKVAGGDNYSDYS
EDLRGFILPQVTYAPDDATSLTVFGLLQSLDQVHVGNGFLPYVGTVEDAPFGKIDRDAYY
SEPDIDEGSYTQQMLGYEFKHDFDNGWTFTQNARYANLHKHEKYPYTYGYVGGAPTGPDY
LLNRIGFEATSKVDSFSIDNRTETDFDLGATTHTFLAGLDYKYYRLDHIQACCGATPISA
TNPVYGTPQGANFVYLDQIVTQQQIGLYAQDQIRFGDGWLVTLNGRYDYVDTKSDAAIGT
SYESNDGAFSGRAGLAYEFDNGLTPYVSAATFFNPLVGTGTSDPSDPTNPAKMVALEPEE
GYQYEAGVKYEPSFIDGLLTASVFQITKQNVSIAVPGFFVNSQLGEVRSRGVELEGKINL
NTNWKIISAFSYTDLEVTEDLNASLIGNTPVLIPETQASLWLDYTVANGTFEGVSLGAGV
RYQGESWADAENTKKVPAATLVDAAIRYEKNDWTASLNVANLFDKEYVAGCQGLQTCGYG
ESRTFTLKLSKKW