Protein Info for SMc01510 in Sinorhizobium meliloti 1021

Annotation: hemin importer ATP-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 PF00005: ABC_tran" amino acids 17 to 169 (153 residues), 95.9 bits, see alignment E=3.4e-31

Best Hits

Swiss-Prot: 100% identical to HMUV_RHIME: Hemin import ATP-binding protein HmuV (hmuV) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 100% identity to smk:Sinme_2478)

Predicted SEED Role

"ABC-type hemin transport system, ATPase component" in subsystem Hemin transport system

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.34

Use Curated BLAST to search for 3.6.3.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92N13 at UniProt or InterPro

Protein Sequence (262 amino acids)

>SMc01510 hemin importer ATP-binding subunit (Sinorhizobium meliloti 1021)
MIRASDISVRLAGRQVLHGISLDAAPGAMTAIVGPNGSGKTTTLKAISGELTPSAGKVTI
NGRDIASLKPWELALKRGVLPQSTVISFPFTVREIVRLGLMANGGEASAHGRIADQALEA
VDLAGFSGRFYQELSGGEQQRVQLARVLCQISAPVAAGEPRYLLLDEPVSSLDIRHQLTI
MRLARQFCADGGGVVAVMHDLNLTSMFADQIVMMKAGRIRARGAPKDVLTDETMEAVFGC
RMRVSVAPAHDIPFVLPQSATM