Protein Info for SMc01494 in Sinorhizobium meliloti 1021

Annotation: phosphoserine phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 295 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR00338: phosphoserine phosphatase SerB" amino acids 75 to 285 (211 residues), 217.7 bits, see alignment E=1.5e-68 TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB" amino acids 83 to 254 (172 residues), 118.6 bits, see alignment E=2.9e-38 PF00702: Hydrolase" amino acids 84 to 255 (172 residues), 58 bits, see alignment E=2.6e-19 PF12710: HAD" amino acids 84 to 252 (169 residues), 79.9 bits, see alignment E=5.2e-26 PF08282: Hydrolase_3" amino acids 219 to 272 (54 residues), 40 bits, see alignment E=5.8e-14

Best Hits

KEGG orthology group: K01079, phosphoserine phosphatase [EC: 3.1.3.3] (inferred from 100% identity to smk:Sinme_2097)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92NR1 at UniProt or InterPro

Protein Sequence (295 amino acids)

>SMc01494 phosphoserine phosphatase (Sinorhizobium meliloti 1021)
MALVATLIANPSNPVLTPARAEAAAERLDASGLYWLADGIACDIVLRDGAEAGEAEARLR
QAVAGAAIDVAVQDAESRRKRFLIADMDSTMIGQECIDELAAEVGLKEKVAAITARAMNG
EIAFEPALVERVALLQGLPVTVVAEVIATRITLTPGGRELIATMKAKGHYSALVSGGFTV
FTGPIAEKLGFDENRANILVEENGKLTGDVARPILGKQAKVDALIDISERLGITPADVIA
VGDGANDLGMLQLAGTGVALHAKPVVADQAKIRIDHGDLTALLYLQGYRKTDFVT