Protein Info for SMc01363 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 PF21102: DprA_N" amino acids 15 to 79 (65 residues), 111.7 bits, see alignment E=1.9e-36 TIGR00732: DNA protecting protein DprA" amino acids 81 to 294 (214 residues), 203.1 bits, see alignment E=1.6e-64 PF02481: DNA_processg_A" amino acids 82 to 285 (204 residues), 215.1 bits, see alignment E=9.9e-68 PF17782: DprA_WH" amino acids 315 to 375 (61 residues), 67.1 bits, see alignment E=1.7e-22

Best Hits

KEGG orthology group: K04096, DNA processing protein (inferred from 100% identity to sme:SMc01363)

Predicted SEED Role

"Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92QL8 at UniProt or InterPro

Protein Sequence (383 amino acids)

>SMc01363 hypothetical protein (Sinorhizobium meliloti 1021)
MPLGGARRTGTALSERQKIAWLRLIRSDNVGPATFRDLISHFGNAEAALEALPELSRRGG
ADRSFRIATVDEAERELEAAHRFGAVFVGIGEPDYPDALRQIDGAPPLLATKGNLNATAR
PSLGIVGSRNASVSGAKFAAMIARDAGAAGYVITSGLARGIDTAAHRASLRTGTIAVLAG
GLDRPYPPENLGLLQEIVSGEGLAVSEMPFGWEPRARDFPRRNRLVAGISLGVAIVEAAN
RSGSLITARYAADFGRLVFAVPGSPLDPRCHGTNDLLKQGATVTTSSADVIEALAPLSRD
DLFSRLEANEPSAEEPRPMPQPPDDTDRSRVVEALGPTPVAIDDLIRYTGLAAPQIHMVL
VELDLAGQLCRHGGNLVSLATAE