Protein Info for SMc01281 in Sinorhizobium meliloti 1021

Annotation: sulfite oxidase subunit YedY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 signal peptide" amino acids 1 to 45 (45 residues), see Phobius details PF00174: Oxidored_molyb" amino acids 89 to 246 (158 residues), 109 bits, see alignment E=1e-35

Best Hits

Swiss-Prot: 100% identical to MSRP_RHIME: Protein-methionine-sulfoxide reductase catalytic subunit MsrP (msrP) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K07147, (no description) (inferred from 100% identity to smk:Sinme_1176)

MetaCyc: 62% identical to protein-L-methionine sulfoxide reductase catalytic subunit MsrP (Escherichia coli K-12 substr. MG1655)
1.8.5.M7 [EC: 1.8.5.M7]; 1.8.5.M7 [EC: 1.8.5.M7]

Predicted SEED Role

"Putative sulfite oxidase subunit YedY"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.5.M7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92QE7 at UniProt or InterPro

Protein Sequence (313 amino acids)

>SMc01281 sulfite oxidase subunit YedY (Sinorhizobium meliloti 1021)
MPSYRAPKIAAAEITPERFFLDRRTFIAAAAGSLALSVPKPSRAAALEASKSTYRADDPA
TPEKDATTYNNFYEFGTGKGDPAANSANFKPAPWTVKVDGLVGKPREFGLEELLAFPLEE
RIYRMRCVEAWSMVIPWIGFPLAALLDRVEPLGSAKYVAFETVVRPEEMPGQSGYFQPLE
WPYREGLRLDEARHPLTILSVGLYGKTLPNQNGAPIRLVVPWKYGFKGIKSIVRISLTET
PPPCTWNLAGPSEYGFYANVNPAVDHPRWSQATENRIGEGGFFGANRRDTLPFNGYAEDV
ASLYAGMDLRVNF