Protein Info for SMc01232 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 42 to 61 (20 residues), see Phobius details amino acids 66 to 92 (27 residues), see Phobius details amino acids 113 to 137 (25 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details TIGR00427: membrane protein, MarC family" amino acids 5 to 203 (199 residues), 183.2 bits, see alignment E=2.4e-58 PF01914: MarC" amino acids 6 to 207 (202 residues), 186.9 bits, see alignment E=1.6e-59

Best Hits

Swiss-Prot: 36% identical to Y972_METJA: UPF0056 membrane protein MJ0972 (MJ0972) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K05595, multiple antibiotic resistance protein (inferred from 100% identity to smk:Sinme_1454)

Predicted SEED Role

"Membrane protein, MarC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Q03 at UniProt or InterPro

Protein Sequence (209 amino acids)

>SMc01232 hypothetical protein (Sinorhizobium meliloti 1021)
MFDVDLLINALTTLLVTLDPPGLAPIFLSLTVGLSRQQRFQVATRGSLIAFFILAAFALF
GDGILGLLGISIGAFRIAGGMLLFWIAFEMIFEKRQERKEKAGETAITKDHLHNIAVFPL
ALPLIAGPGAISATILLGSSFPSALERVQLIVVIAASMAILFLALVIAERIDRFLGVTGR
AILTRLLGVILAALAVQFVVDGVRSAFQV