Protein Info for SMc01220 in Sinorhizobium meliloti 1021

Annotation: lipopolysaccharide core biosynthesis glycosyl transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF13439: Glyco_transf_4" amino acids 12 to 148 (137 residues), 34.1 bits, see alignment E=8.5e-12 PF00534: Glycos_transf_1" amino acids 158 to 316 (159 residues), 123.6 bits, see alignment E=2e-39 PF13692: Glyco_trans_1_4" amino acids 169 to 304 (136 residues), 106.1 bits, see alignment E=5.7e-34 PF13524: Glyco_trans_1_2" amino acids 246 to 327 (82 residues), 36.4 bits, see alignment E=1.5e-12

Best Hits

Swiss-Prot: 100% identical to LPSE_RHIME: Lipopolysaccharide core biosynthesis glycosyltransferase LpsE (lpsE) from Rhizobium meliloti (strain 1021)

KEGG orthology group: None (inferred from 99% identity to smk:Sinme_1466)

Predicted SEED Role

"PUTATIVE LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS GLYCOSYL TRANSFERASE PROTEIN( EC:2.- )"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q9R9N1 at UniProt or InterPro

Protein Sequence (340 amino acids)

>SMc01220 lipopolysaccharide core biosynthesis glycosyl transferase (Sinorhizobium meliloti 1021)
MKVTHFHFGKDGGAERFFVHLVNALAERGVEQTAIIRPGRGWRRDIEGAAKIRESHFRNL
SLDRILLPLKVKHMARREKPDVLMAWAPRASELMPNYKGAFKISRLGDYPTRLSYFRNTD
CIVCNTPGIAERVSDLGWKREIRVISNFTGTGRVVAVDRAKLDTPADAPVVMSMGRFVER
KGFHTLIEAVARLPGVYLWLLGDGEERDNLHKLATDLGVSGRVRFAGWQDDTRPFLAAVD
VFVMSSSHEPLGNVILESWAQGTPVVSTRSEGPQWFMRDGENGLMVDIGDAEGFARAIEQ
IVADNSLRTRLAERGHETLVGQFSREAITDAYLQLLASKP