Protein Info for SMc01090 in Sinorhizobium meliloti 1021

Annotation: ATP-dependent RNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details PF00270: DEAD" amino acids 24 to 194 (171 residues), 142.1 bits, see alignment E=2.1e-45 PF00271: Helicase_C" amino acids 234 to 339 (106 residues), 93 bits, see alignment E=2.2e-30 PF03880: DbpA" amino acids 470 to 540 (71 residues), 52.9 bits, see alignment E=4.5e-18

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 100% identity to sme:SMc01090)

Predicted SEED Role

"FIG003033: Helicase domain protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92SG6 at UniProt or InterPro

Protein Sequence (630 amino acids)

>SMc01090 ATP-dependent RNA helicase (Sinorhizobium meliloti 1021)
MTEFAGIAPAIAEALAKRGYETLTPVQQAMLDPSLGTADALVSAQTGSGKTVAFGLALAP
TLIGSARKFAQAGAPLALVIAPTRELALQVMRELDWLYEMAGATIASCVGGMDMRSERRT
LERGAHIVVGTPGRLCDHIRRGSLDISGLKAVVLDEADEMLDLGFREDLEFILEASPADR
RTLMFSATVPRSIATLAKSYQRDAVRIGVTSEQKQHGDIEYRSLLVAPSDRENAIINVLR
FYEARNAIVFCSTRAAVNHLTARFNNRGFSVVALSGELSQNERTHALQAMRDGRARVCIA
TDVAARGIDLPGLELVIHADLPTNSDTLLHRSGRTGRAGQKGVSALIVPVNARRKAERLL
ENARITAAWAKPPLADEVARRDDERIAADPALAEAPREDEQAIVETLISRYGAEKIAAAF
VRQFRSNRSAPEELVDVAVYDDRRKPRRDGPAFTGDSEPAPRADFADGQWFSLSVGRKQN
AEPRWLIPMLCRYGKLSKRDIGAIRMQPEETYVEMTADGAERLLAAIGPNRMLEKGIRVK
TLPGAPDSSRPRQDKPDFEKKRPPATAAEREHKDFEPKRKFDKQPPVAQDAHSDSRGDKP
WSKKKGKPEAQKTGDFKPGAKRNNAKKRQP