Protein Info for SMc00973 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 TIGR00478: TlyA family rRNA methyltransferase/putative hemolysin" amino acids 10 to 243 (234 residues), 186.2 bits, see alignment E=2.9e-59 PF01479: S4" amino acids 10 to 48 (39 residues), 37.6 bits, see alignment 1.4e-13 PF01728: FtsJ" amino acids 65 to 249 (185 residues), 134.2 bits, see alignment E=5.2e-43

Best Hits

KEGG orthology group: K06442, putative hemolysin (inferred from 100% identity to sme:SMc00973)

Predicted SEED Role

"RNA binding methyltransferase FtsJ like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92RJ2 at UniProt or InterPro

Protein Sequence (251 amino acids)

>SMc00973 hypothetical protein (Sinorhizobium meliloti 1021)
MSQDTQMTIRLDQLLLNRGLVASRARARDAIQRGTVKVDGRTVTKPASTFAQGVTLTIDD
PAQDYVSRAALKLVAALDHFGLDPSEQTCLDVGASTGGFTEVLLKRGAAHVVAVDVGHGQ
IHPRVAEDPRVTNIEGLNARSMTRGDIDERAITFIVSDVSFISLKLALPPALGLAEPGAC
CILLVKPQFEAGRDAISKAGLLKDPESAPAVAAELERWLVEDMGWRSLGLIPSPIAGGDG
NSEFLLAGRKP