Protein Info for SMc00922 in Sinorhizobium meliloti 1021

Annotation: transporter transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 41 to 76 (36 residues), see Phobius details amino acids 106 to 107 (2 residues), see Phobius details amino acids 109 to 132 (24 residues), see Phobius details amino acids 150 to 169 (20 residues), see Phobius details amino acids 181 to 204 (24 residues), see Phobius details amino acids 230 to 250 (21 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 312 to 335 (24 residues), see Phobius details amino acids 355 to 372 (18 residues), see Phobius details amino acids 378 to 401 (24 residues), see Phobius details amino acids 422 to 445 (24 residues), see Phobius details amino acids 451 to 472 (22 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 18 to 444 (427 residues), 248.9 bits, see alignment E=4.7e-78

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 100% identity to sme:SMc00922)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92RR9 at UniProt or InterPro

Protein Sequence (485 amino acids)

>SMc00922 transporter transmembrane protein (Sinorhizobium meliloti 1021)
MTIPPGASPQLYNEDLAPAKERNWGAFSIFNVWTSDVHSLWGYYLAASLFLFCGSFMNFL
LAIGIGSLIIFFLMQLVGVAGVRTGVPFPVLARASFGIWGANFPAIVRAIVACFWYGAQT
AAASGAIVALLVRNESLLQFHQSSHMLGHSTLELVCYVVVWGLQLLIIQNGMETVRKFQD
WAGPAVWVMMLLLAIYLVVKAGGFSFSHTIPMDALLEKTKNAGVPGVPGSFAALGAVAAI
WVTYFSALYLNFCDFSRYCPSERSLKVGNLWGLPVNLILFSLVAGVTTIAAFNVYGEVLL
HPDQISAKFDSWFLALLAALTFAVATLGINVVANFVSPAFDFANVFPKHIDFKKGGYIAA
LIALALYPFAPWEGGAAHFVNMIGNTMGPIFGVMMVDYYLIRKGRVDVEALYREDGEFRF
ENGWHVNALVAAGIGIVFSSILPGLTSVMPAWWGVYGWFFGVAIAGAIYYALRSFKSARP
YPAQP