Protein Info for SMc00879 in Sinorhizobium meliloti 1021

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 PF09339: HTH_IclR" amino acids 19 to 68 (50 residues), 39.8 bits, see alignment 3e-14 PF01614: IclR" amino acids 132 to 257 (126 residues), 111.6 bits, see alignment E=2.5e-36

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMc00879)

Predicted SEED Role

"D-galactonate regulator, IclR family" in subsystem D-galactonate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92RN5 at UniProt or InterPro

Protein Sequence (284 amino acids)

>SMc00879 transcriptional regulator (Sinorhizobium meliloti 1021)
MKQKKEDDMEGDPAGTGTLGKAMAVLEAVAMADRPQRFTDILQTVRQPRGTLHRLLGHLV
EEGLLVQRRDLSYEPGLRLLKFAYRSWSGNRFREIAAPYLLHLHQLTGETVHLGLLREAE
IIYVDKVESRQTVRMSSQIGKASPAYCTGIGKAALSVLPGGELQRISTGMEFHPFTAQTH
RSIESLLAEIEEIRHDGHAFDREEHEAEICCVAAPISVPEHDLVGGISVTGPSYRVSFKQ
LTAWAQDVRKVAAEIEEEVRIRLGPGRETGAAAPRVLSDAQRSQ