Protein Info for SMc00874 in Sinorhizobium meliloti 1021

Annotation: magnesium/cobalt transporter CorA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 240 to 258 (19 residues), see Phobius details amino acids 265 to 288 (24 residues), see Phobius details amino acids 300 to 320 (21 residues), see Phobius details PF01544: CorA" amino acids 26 to 322 (297 residues), 176.9 bits, see alignment E=3.1e-56

Best Hits

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 100% identity to smk:Sinme_0538)

Predicted SEED Role

"Magnesium and cobalt transport protein CorA" in subsystem Campylobacter Iron Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92RN1 at UniProt or InterPro

Protein Sequence (326 amino acids)

>SMc00874 magnesium/cobalt transporter CorA (Sinorhizobium meliloti 1021)
MITGYCVNGETVALSTAEPPSALRPDLVWIDLVEPTKAEDLMIEGLLGIPIPTRDDLRDI
EPSSRLYTDDGAVFMTASLVYRSDTEMPGLTDVGFILAGKCLVTVRYAEPRAFGLFKAGM
HRIPGGCRNGAVILTRLLETIVDRTAEILEQAVDRIDDLALQVFGDKTSGRRHRPPHFLE
ARLRDVAGHHRLVAKTRDSLASLSRLLTFVYTVPDVQADKETRELCRTVSRDIQSLSEHT
AFISGNITFLLDASLGLINVEQNAIIKIFSIASVVLLPPTLVASVYGMNFRIMPELEWQF
GYPWALAAMVLSAVIPFFFFRWKGWL