Protein Info for SMc00819 in Sinorhizobium meliloti 1021

Annotation: catalase hydroperoxidase HPII(III) protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 8 to 391 (384 residues), 606.9 bits, E=1.7e-186
• PF06628: Catalase-rel
  • amino acids 419 to 478 (60 residues), 59.1 bits, E=3.8e-20

Best Hits

Swiss-Prot: 100% identical to CATA_RHIME: Catalase A (katA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 100% identity to smk:Sinme_0473)

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• reactive oxygen species degradation (3/4 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6

Sequence Analysis Tools

See P95631 at UniProt or InterPro

Protein Sequence (494 amino acids)

>SMc00819 catalase hydroperoxidase HPII(III) protein (Sinorhizobium meliloti 1021)
MTDRPTITTTAGAPVPDNQNSLTAGPRGGIMLQDYQLIEKLAHQNRERIPERVVHAKGWG
AFGSLKITGDISQYTRAKCLQPGAETPMLARFSTVAGEQGAADHERDVRGFALKFYTDEG
NWDLVGNNTPVFFIRDPYKFPDFIHTQKRHPKTNLRSATAMWDYWSLSPESLHQVTILMS
DRGLPQTPMHMNGYGSHTYSFWNDAGERYWVKFHFKTQQGHKFFTNEEGEAVIGKTREGY
QESLFYAIENGEFPRWTVQVQIMPELDVEKTPYNPFDLTKVWPHADYPPVEIGVLELNRN
PENYFAEIENAAFSPSNIVPGIGFSPDKVLQARIFSYADAHRYRLGTHYEHIPVNQPRCP
VHHYHRDGQMNTYGGIRTGNPDAYYEPNSFNGPAEQPLAKEPPLRIDGDMSRYDHRVGND
DYVQVRALFGLFDEGQKSRLFSNIAAAMGGVPGEIIERQLIHFARVHPEYEAGVRQALKT
AHGYEADTISTAAE