Protein Info for SMc00609 in Sinorhizobium meliloti 1021

Annotation: anaerobic dimethyl sulfoxide reductase subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04879: Molybdop_Fe4S4
  • amino acids 15 to 67 (53 residues), 28 bits, 2.6e-10
• PF00384: Molybdopterin
  • amino acids 70 to 482 (413 residues), 130.6 bits, E=1.1e-41
• PF01568: Molydop_binding
  • amino acids 588 to 692 (105 residues), 66.2 bits, E=4e-22

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMc00609)

Predicted SEED Role

"Anaerobic dehydrogenases, typically selenocysteine-containing" in subsystem Anaerobic respiratory reductases

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

Sequence Analysis Tools

See Q92QW6 at UniProt or InterPro

Protein Sequence (704 amino acids)

>SMc00609 anaerobic dimethyl sulfoxide reductase subunit A (Sinorhizobium meliloti 1021)
MNVATPIRQEKTIGHSVCPHDCPSACALEVDLTAEGRIGRVRGAAENTYTAGVICAKVAR
YAERIYHPGRLMVPQRRVGAKGEGRWQEISWETALDEIADQFVKAEQRHGSEAVWPYFYA
GTMGQVQRDSIERLRHAKRYSGFFGSICTNMAWTGYTMGTGTLRGPDPREMAKSDCVVIW
GTNAVATQVNVMTHAVKARKERGAKIVVIDVYDNPTIKQADMGLVLKPGTDAALACAVMH
VAFRDGHAGRAYMAEFADDPAGLEAHLKTRGPEWASAITGLSVEEIEAFARLVGTTPRTY
FRLGYGFTRQRNGSVAIHAAASVATVLGSWKHEGGGAFHSNNDIFRLDKRELVGSAFHDP
DVRMLDQSQIGRVLTGDAEALRHRGPVTALLIQNTNPVNVAPEQRLVKRGFLRDDVFVAV
HEQFMTDTAQLADIVLPATMFLEHDDLYRGGGHQHILLGPKVVEPPPTVRTNLFVIEELA
KRLGVADCPGFRLTERQHIDQLLANYGIGYDEMKERKWLDCQPAFDEAHFLNGFGHPDGR
FRFKADWTGTPAPNRPPKAMGAQGPHGQLPEFPDHVDLIEVADERHPFRLATSPARSFLN
STFAETPSSIQKEGRPEVMIHAEDAAELGIAEGDVVRLGNGRGEIRLHAKIGGGTRRGVV
IAEGLWPNGAHLDGEGINVLTGADAVAPYGGAAFHDNRVWMRRA