Protein Info for SMc00604 in Sinorhizobium meliloti 1021

Annotation: outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13505: OMP_b-brl" amino acids 33 to 212 (180 residues), 74.9 bits, see alignment E=9.7e-25 PF01389: OmpA_membrane" amino acids 50 to 183 (134 residues), 28.7 bits, see alignment E=1.1e-10

Best Hits

Swiss-Prot: 52% identical to ROPB_RHILV: 22 kDa outer membrane protein (ropB) from Rhizobium leguminosarum bv. viciae

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_0970)

Predicted SEED Role

"Surface antigen"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92QX0 at UniProt or InterPro

Protein Sequence (212 amino acids)

>SMc00604 outer membrane protein (Sinorhizobium meliloti 1021)
MRTLTTTLMASAMALVAFQAAHAADVVDEVPAAPAAEYTEPAVRNWSGAYVGGTIDWHHG
EADATGNNKSVGFGGGLYGGYNVQDGQMVYGGEADVNYTGNDSRSSGRRVKQGVNGSVRG
RVGVDLNPVLVYGTAGVALGNAKLSTPAGSDDKTLVGWTAGVGAETFVTDNITARAEYRY
TDYGSKDFRAGGSTISSGYDEHSVKLGMGVKF