Protein Info for SMc00551 in Sinorhizobium meliloti 1021

Annotation: phosphatidylserine decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00164: phosphatidylserine decarboxylase homolog
  • amino acids 15 to 221 (207 residues), 202.3 bits, E=2.8e-64
• PF02666: PS_Dcarbxylase
  • amino acids 46 to 217 (172 residues), 156.1 bits, E=4.8e-50

Best Hits

Swiss-Prot: 100% identical to PSD_RHIME: Phosphatidylserine decarboxylase proenzyme (psd) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K01613, phosphatidylserine decarboxylase [EC: 4.1.1.65] (inferred from 100% identity to sme:SMc00551)

Predicted SEED Role

"Phosphatidylserine decarboxylase (EC 4.1.1.65)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 4.1.1.65)

MetaCyc Pathways

• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• phosphatidylserine and phosphatidylethanolamine biosynthesis I (2/2 steps found)
• cardiolipin and phosphatidylethanolamine biosynthesis (Xanthomonas) (3/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (9/13 steps found)
• superpathway of phospholipid biosynthesis II (plants) (12/28 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.65

Sequence Analysis Tools

See Q9FDI9 at UniProt or InterPro

Protein Sequence (232 amino acids)

>SMc00551 phosphatidylserine decarboxylase (Sinorhizobium meliloti 1021)
MSLIDTVRNTLVPVHREGYRFIAIFFVVSLALGFLWEPLMWIGFVLTAWCAYFFRDPERM
TPIDDDLVISPADGTVSSVATVMPPEELGLGSEPMLRISVFMNVFNCHVNRAPMGGTVRR
IAYRAGKFVNAELDKASQENERNGLVIETKHGQIGVVQIAGLVARRILCWTRESASLEAG
ERFGLIRFGSRLDVFLPAGAEPRVTVGQTATGGETVLAEFGSAKGPVISRRA