Protein Info for SMc00525 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1138 transmembrane" amino acids 55 to 77 (23 residues), see Phobius details PF13116: YhdP" amino acids 382 to 798 (417 residues), 51.3 bits, see alignment E=2.6e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMc00525)

Predicted SEED Role

"Large exoproteins involved in heme utilization or adhesion"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92KB6 at UniProt or InterPro

Protein Sequence (1138 amino acids)

>SMc00525 hypothetical protein (Sinorhizobium meliloti 1021)
MGQSGRTLVPMTEIRGEKVDFRREDIVALHALPSAQAHDPVIVHTPRPGGAWRLCARLFL
CCSLLVFIAVASLVAIIESGIVDGPLNARARTALNAALGQGYSADVESTVIRLTGGGALA
LKARGVTLKESGSGRHLARLGAISIALDPFALATGRIDVSRLEAEGGELDTGLLPRGEPI
DLTAIRIADVGNALEELFAQGDRMSRLTAGRATQTVVLSNFSLKVSGVRGRVVPVEIKTL
EFSHDPDSSMRVDGTIAVDGTESLLTAKALGNNGRIAAFEARLDALSLSPFLYHGKSAKE
EAFGIEAAADVTLNAARATDGKKPALTATVKTSKGAFHAGGLVSTLNSSDLNLSYDFERA
SVEILSSMVRIGRSSFPFTGALIDLDKVAGADRKGFAVDLLLKNASSDPEDLQERPLAFD
AKASGRFESDSHRLIFDQLAISSPLGSMAGSLSVAFGKTSPRISFAALSDRMHSRVVKQL
WPWWLAKGARRWALANLYGGTVTDARIEVSIPEGRIASSGGELRLNERELNINFAIDDTR
INIAGEIPPLRDTAGHFSLSGERMSVAVKKGAAFFPSGHSVALNGGDFVIADVYSKPLMA
EMKIEVAGQADAIAELVRYKPIQALQKTPFTPEDFTGPMKALVGARFGLISGQKPPPPLW
QVEMQLENVTIKRPIAGRSIANLDGTMRIDNERAVLQANALIDGAKMRIALTEPVDASAN
VKRTREISGTLDEAARAKIAPALSGMVSGPVGIDVSLAEDGSQSVKADLGKAVLSLPWIG
WSKGSGIAAEAHFTIRATGGITEINDFHLTGEGFGGNGELRVDESGLASARLGGVRLASG
DDFAVTVDRSRGGYSIDLTGTAADIRPALARVKGGAAAKDGGNVKINARLDRVTGFNGEV
LSNVNLAYSSRGQQIDDVDLSAVTASGQAVVARLVKAGADNTLELTTSDAGAFARFIDIY
RNMRGGLLNLRLRDRGANSWRGTVDIRKFSLVGEQRLQSMVSTPAGQDGRSLNQAVRRDI
DVSTAQFERGFAQLLLDQGAIRVGSGVVRGVDVGATFQGTVRDSNGRMDMTGTFMPAYGL
NRLFGELPLIGVLLGNGRDRGLLGITFKLTGPFSQPNLTINPLSIIAPGVFRNIFEFQ